Articles Posted in ‘Ovarian cancer’

Overview of the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial

In 1993, the National Cancer Institute launched one of the largest cancer screening trials ever planned in the United States, in an effort to answer the question of screening efficacy in four cancers: prostate, lung, colorectal, and ovarian. Ten centers across the country ultimately accrued more than 150,000 men and women for this study. Nineteen years after it began, PLCO has now released the trial’s final major outcome finding, for colorectal cancer.

Ovarian Cancer Treatment: Where We Are Now

Shown are surgeons and a nurse performing surgery

Ovarian cancer has proven to be a very difficult cancer to diagnose at a curable stage and thus treat successfully.  Even though it has one of the highest mortality rates of all gynecological cancers in the United States, there are no validated or proven screening tests, making it a challenge to diagnose at an early [...]

Measles viruses genetically modified to treat ovarian cancer

Scientists prepare clinical lots of measles virus to use in clinical trials against cancer. Credit:  Mayo Clinic.

The Cancer Genome Atlas (TCGA) is undertaking a large-scale review of cancer genes. The most recent study results were published June 30, 2011, in Nature. As part of this work, TCGA investigators searched for existing drugs that might inhibit genes that were suggested to play a role in ovarian cancer. The search identified 68 genes [...]