Articles Posted in ‘screening’

NCI scientists identify new gene mutation that predisposes families to melanoma

 Chromosomes with irregular teleomeres in a person with melanoma who carried the POT1 mutation. Image generated by quantitative Fluorescent in situ hybridization (FISH).

NCI scientists and their colleagues have identified a rare inherited mutation in a gene that can increase the risk of familial melanoma.

Sequencing techniques uncover mutations in genes that can increase cancer risk

Device on benchtop in lab, featuring open lid for placement of microarray chip and to the right, a read-out screen.

Sequencing the human genome was just the beginning—now that the findings from that landmark effort are widely available, scientists are working to put that data to work to understand the genetic causes of many diseases, including cancer, by using the latest sequencing techniques.

Microbes within our bodies may cause or contribute to cancer

Salmonella typhi_Credit CDC

The Human Microbiome Project (HMP) investigators will sequence, at minimum, 3,000 bacterial genomes that represent the human microbiome. To date, there are more than 1,000 bacterial genomes at various stages of sequencing.